Mesodma is an extinct genus of mammal, a member of the extinct order Multituberculata within the suborder Cimolodonta, family Neoplagiaulacidae. It lived during the upper Cretaceous and Paleocene Periods of what is now North America. The earliest record is from the late Santonian age rocks of the Straight Cliffs Formation.[1]
The species "Mesodma" primaeva from the Judithian of Western Interior of North America was formerly assigned to the genus Mesodma, but subsequently it was made the type species of a separate genus Filikomys.[3]